Featured Molecules & Platforms
Our technology portfolio spans high-growth therapeutic areas — with full-stack support from clone development through commercial-scale manufacturing and regulatory filing.
Semaglutide
A long-acting GLP-1 receptor agonist used in Type 2 Diabetes and obesity management — one of the fastest-growing therapeutic segments globally.
- Clone development & high-density fermentation
- Upstream & downstream purification process
- Chemical synthesis conjugation & fatty acid chain attachment
- Analytical method validation & ICH characterization package
Human Growth Hormone (Somatropin)
A recombinant human growth hormone used widely in endocrinology and pediatric/adult metabolic disorders, with strong and sustained global demand.
- Clone development & high-titer fermentation
- Inclusion body isolation, solubilization & refolding optimization
- Multi-step chromatography & final bulk preparation
- Formulation stability & commercial scale-up support
Pembrolizumab
A humanized IgG4 monoclonal antibody targeting PD-1 (Programmed Cell Death Protein 1), with landmark approvals across immuno-oncology for multiple solid tumors.
- High-producing CHO cell line development & feed optimization
- Protein A affinity capture, viral inactivation & polishing chromatography
- Full biosimilarity physicochemical & functional characterization
- Regulatory CMC dossier preparation & single-use bioreactor scale-up
Brazzein
A naturally occurring 54-amino-acid sweet protein isolated from the West African plant Pentadiplandra brazzeana. Up to 2,000× sweeter than sucrose with zero calories, exceptional heat and pH stability, and no glycemic effect.
- E. coli recombinant expression (soluble, disulfide-intact structure)
- Proof-of-Concept completed at 8L fermentation scale
- Single-step chromatography purification with high recovery
- ENK enzyme digestion & HPLC analytical method validated
- LC-MS intact mass characterization; target yield >1.8 g/L
- GRAS regulatory safety strategy & scale-up roadmap